Last edited by Zulkinos
Monday, July 27, 2020 | History

2 edition of Apoptosome found in the catalog.

Apoptosome

Francesco Cecconi

Apoptosome

an up-and-coming therapeutical tool

by Francesco Cecconi

  • 193 Want to read
  • 6 Currently reading

Published by Springer in Dordrecht, New York .
Written in English

    Subjects:
  • Therapy,
  • Apoptosis,
  • Therapeutic use,
  • Neoplasms,
  • Physiology,
  • Apoptosomes

  • Edition Notes

    Includes bibliographical references and index.

    StatementFrancesco Cecconi, Marcello D"Amelio, editors
    Classifications
    LC ClassificationsQH671 .A667 2010
    The Physical Object
    Paginationx, 322 p. :
    Number of Pages322
    ID Numbers
    Open LibraryOL25304174M
    ISBN 109048134145, 9048134153
    ISBN 109789048134144, 9789048134151
    LC Control Number2009941845
    OCLC/WorldCa502401090


Share this book
You might also like
Media three for Christian formation.

Media three for Christian formation.

Intensive egg and chicken production

Intensive egg and chicken production

Newsletter

Newsletter

Mariner to Mars

Mariner to Mars

The new art of letter-writing

The new art of letter-writing

Americas Pioneer Mallet Old Maud - A Life & Times

Americas Pioneer Mallet Old Maud - A Life & Times

Mysterious Powers

Mysterious Powers

Between shadows

Between shadows

Address of the ... association on the treatment and prevention of crime

Address of the ... association on the treatment and prevention of crime

Beaver Bank Presbyterian Church, opened on December 1st, 1888, United Church of Canada since 1925

Beaver Bank Presbyterian Church, opened on December 1st, 1888, United Church of Canada since 1925

Mr. Pepys

Mr. Pepys

Skill formation in the informal sector

Skill formation in the informal sector

Sexuality and the person with traumatic brain injury

Sexuality and the person with traumatic brain injury

The Promise

The Promise

Apoptosome by Francesco Cecconi Download PDF EPUB FB2

Apoptosome: An up-and-coming therapeutical tool - Kindle edition by Francesco Cecconi, Marcello D'Amelio. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Apoptosome: An up. Helen M.

Beere, Douglas R. Green, in Kelley and Firestein's Textbook of Rheumatology (Tenth Edition), The Apoptosome-Activation Platform for Procaspase Procaspase-9 is rendered catalytically active by its recruitment to a large protein complex called the apoptosome, comprising procaspase-9, apoptotic protease activating factor-1 (APAF-1), and additional regulatory proteins.

31,32 APAF. "Apoptosome" is the first book that presents a concise synthesis of recent developments in the understanding of how the Apoptosome book of the cell death cascade is handled by a cytosolic signalling platform known as the apoptosome.

The book also discusses how insights into the regulation of apoptosome may be exploited for designing new drugs aimed. "Apoptosome" is the first book that presents a concise synthesis of recent developments in the understanding of how the activation of the cell death cascade is handled by a cytosolic signalling platform known as the apoptosome.

The book also discusses how insights into the regulation of apoptosome. Guy S. Salvesen, in Handbook of Cell Signaling (Second Edition), Initiator Caspases. At the cytosolic concentration in human cells (apoptosome to become active–reviewed in [27].Significantly, unlike the executioner caspases 3 and 7, pro-caspase 9 does not need to be cleaved in the linker region to.

"Apoptosome" is the first book that presents a concise synthesis of recent developments in the understanding of how the activation of the cell death cascade is handled by a cytosolic signalling platform known as the apoptosome.

The book also discusses how insights into the regulation of apoptosome may be exploited for designing new drugs aimed Brand: Springer Netherlands.

Apoptosomes from different organisms vary widely in their structure, and how they perform their jobs. The human apoptosome is composed of seven subunits and is activated by cytochrome c. The one from fruit flies, known as DARK (PDB entry 3iz8), has eight subunits, and may or may not need cytochrome c.

Caspases and the apoptosome. The caspases are a family of proteins that are one of the main executors of the apoptotic process. They belong to a group of enzymes known as cysteine proteases and exist within the cell as inactive pro-forms or zymogens.

These zymogens can be cleaved to form active enzymes following the induction of apoptosis. The apoptosome recruits and activates caspases that cleave intracellular substrates and ultimately lead to cell death by apoptosis.

Release of mitochondrial cytochrome-c into the cytoplasm results in binding with monomers of Apaf-1, thereby inducing a conformational change that permits a stable association with (deoxy)adenosine triphosphate and.